Figure 1.

(A–C) Measurement of tissue NAE levels. The levels of AEA, OEA, and PEA in normal myometrium (myometrium; n=19), normal myometrium adjacent to fibroid (adjacent; n=19) and within fibroid tissue (n=19) were evaluated by ultra-high-performance liquid chromatography-tandem mass spectrometry. The data for each patient biopsy is presented together with the mean ± standard deviation for the measurement. Statistical differences in NAE levels between normal and adjacent myometrium were determined by unpaired Student’s t-test and by paired Student’s test between adjacent myometrium and fibroid: * P<0.05; n.s. – not significantly different.