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. 2019 Mar 7;25:76–87. doi: 10.12659/MSMBR.914019

Table 2.

The expression of components of the endocannabinoid system in the normal myometrium and fibroid tissue.

CB1 CB2 CB1: CB2 TRPV1 GPR55 NAPE-PLD FAAH NAPE-PLD: FAAH
Myometrium 2.0±1.1 0.9±0.5 2.22±1.22 3.7±0.8 5.6±3.3 14.1±2.0 1.3±0.5 10.8±1.54
Fibroid 0.6±0.2ns 2.2±0.7ns 0.27±0.09* 4.6±2.1ns 1.1±0.3ns 12.5±3.8ns 0.5±0.1* 25.0±4.6*

The data are presented as mean ±SEM from 10 normal myometrial and 20 fibroid tissue samples. In each case, the levels of the indicated transcripts were normalized to the geometric mean of the amount of transcript for the β-actin (ACTB), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein ζ (YWHAZ) and splicing factor 3a, subunit 1 (SF3A1) housekeeping genes: (see Material and Methods section).

*

P<0.05;

ns – not significantly different, fibroid versus normal myometrium; Student’s unpaired t-test.