FIG. 3.

Increased perivascular immunoglobulin (Ig)G effusion in the brain post-blast and by incorporation of polyurea-coated cylinders. (A) Representative microscopic images exhibiting IgG immunoreactivity in different brain regions at 24 h post-blast or post-sham blast. Scale bar is 50 μm. (B) Quantification of the percentage of the cerebral cortex area that was immunopositive for IgG. There was a significant, 700% increase in rat cortical IgG immunostaining following blasts generating 2300g compared with sham animals (**p < 0.01, n = 5) and a 100% increase compared with the area present following blasts with vehicles that incorporated polyurea-coated cylinders (*p < 0.05; n = 6).