Table 2.
Association Between Single Highest Ever Duration of Breastfeeding Reported Across All Live Births (HIGH-EVER) and Coronary Artery Disease Status Using Logistic Regression, Before and After Covariate Adjustment and Multiple Imputation of Missing Covariates
UnadjustedOR (95% CI) | pb | Complete caseOR (95% CI)a | pb | Multiple imputationOR (95% CI)a | pb | |
---|---|---|---|---|---|---|
Maximum duration of breastfeedingc | ||||||
Ref: never child/pregnant | ||||||
1+ child; never breastfed | 2.32 (1.18–4.57) | 0.01 | 1.79 (0.81–3.94) | 0.06 | 1.75 (0.82–3.71) | 0.04 |
1–4 months | 2.51 (1.43–4.42) | 2.78 (1.43–5.39) | 2.62 (1.4–4.91) | |||
5–9 months | 1.1 (0.58–2.06) | 1.04 (0.5–2.15) | 1.02 (0.51–2.02) | |||
10–18 months | 1.14 (0.64–2.02) | 1.22 (0.63–2.37) | 1.3 (0.69–2.44) | |||
19+ months | 1.64 (0.81–3.33) | 1.72 (0.69–4.26) | 2.04 (0.93–4.5) | |||
Maximum duration of breastfeedingd | ||||||
Ref: child +, never breastfed | ||||||
1–4 months | 1.08 (0.51–2.3) | 0.06 | 1.57 (0.63–3.92) | 0.14 | 1.5 (0.62–3.59) | 0.12 |
5–9 months | 0.47 (0.21–1.06) | 0.53 (0.2–1.39) | 0.52 (0.21–1.29) | |||
10–18 months | 0.49 (0.23–1.05) | 0.71 (0.29–1.76) | 0.77 (0.32–1.84) | |||
19+ months | 0.71 (0.3–1.68) | 0.89 (0.29–2.76) | 1.12 (0.41–3.07) | |||
Maximum duration of breastfeedinge | ||||||
Ref: 1–4 months | ||||||
5–9 months | 0.44 (0.21–0.89) | 0.06 | 0.33 (0.14–0.8) | 0.09 | 0.34 (0.15–0.79) | 0.07 |
10–18 months | 0.45 (0.23–0.88) | 0.47 (0.21–1.06) | 0.53 (0.25–1.14) | |||
19+ months | 0.65 (0.3–1.43) | 0.57 (0.2–1.65) | 0.76 (0.31–1.9) |
Adjusted for age, race, BMI, tobacco use, hypertension, systolic BP, hyperlipidemia, total cholesterol, HDL, triglycerides, and diabetes.
Wald chi-square test for breastfeeding variable.
In complete case models, 65 of 643 observations deleted because of missing data.
In complete case models, 41 of 382 observations deleted because of missing data.
In complete case models, 37 of 332 observations deleted because of missing data.