Table 2.
Health state | Visual analog scale1 | Standard Gamble2 | ||||
---|---|---|---|---|---|---|
Score | Score | % risk of developing cancer | ||||
Median (range) | SD | Median (range) | SD | Median (range) | SD | |
Perfect Health (VAS only) | 1.00 (.80, 1.00) | .05 | N/A | N/A | N/A | N/A |
Current Health (VAS only) | .85 (.40, .99) | .11 | N/A | N/A | N/A | N/A |
Death (VAS only) | .00 (.00, 1.00) | .11 | N/A | N/A | N/A | N/A |
Chemoprevention with oral contraceptives | .85 (.00, 1.00) | .29 | .80 (.00, 1.00) | .30 | 20.0 (0.0, 100.0) | 29.79 |
Annual colonoscopy | .90 (.10, 1.00) | .22 | .78 (0.00, 1.00) | .24 | 22.5 (0.0, 100.0) | 24.15 |
Biannual colonoscopy | .85 (.00, 1.00) | .23 | .80 (.10, 1.00) | .20 | 20.0 (0.00, 90.0) | 19.62 |
Annual endometrial biopsy, transvaginal ultrasound, CA 125 | .90 (.10, 1.00) | .20 | .70 (.30, 1.00) | .20 | 30.0 (0.0, 70.0) | 19.70 |
Biannual endometrial biopsy, transvaginal ultrasound, CA 125 | .80 (.00, 1.00) | .21 | .80 (.40, 1.00) | .17 | 20.0 (0.0, 60.0) | 17.21 |
Annual combined screening consisting of colonoscopy and endometrial biopsy, transvaginal ultrasound, CA 125 | .98 (.10, 1.00) | .16 | .75 (.20, 1.00) | .23 | 22.5 (0.0, 80.0) | 23.27 |
Biannual combined screening colonoscopy and endometrial biopsy, transvaginal ultrasound, CA 125 | .85 (.00, 1.00) | .22 | .80 (.30, 1.00) | .18 | 20.0 (0.0, 70.0) | 18.27 |
Prophylactic HYST/BSO (pre-menopausal) | .50 (.00, 1.00) | .32 | .40 (0.00, 1.00) | .28 | 60.0 (0.0, 100.0) | 28.34 |
Prophylactic HYST/BSO (post-menopausal) | .85 (.00, 1.00) | .26 | .60 (0.00, 1.00) | .26 | 40.0 (0.0, 100.0) | 26.18 |
SD=standard deviation
Visual analog scale: Health states were ranked from 0 (least preferred) to 100 (most preferred). Preference scores were calculated by dividing the number corresponding to health state rankings by 100 (i.e., 75/100 = .75). Scores closer to 1.0 reflect more favorable health states.
Standard gamble: Scores for health states were calculated by subtracting patients’ stated threshold of lifetime disease risk from 100% and dividing that difference by 100 to arrive at a score on a 0.0 to 1.0 scale (0.0 = least favorable; 1.0=most favorable). Percent risk of developing cancer was defined as the threshold of lifetime risk of endometrial and colorectal (0% to 100%) at which patients would consider undertaking the risk management strategy depicted in each health state.