TABLE 2. Pulmonary function test results, fibrotic scores, ESS scores, and polysomnographic parameters of the included patients.
| Variables | All patients (n = 49) | Patients with OSA (n = 34) | Patients eligible for PAP treatment (n = 25) |
|---|---|---|---|
| AHI (events/h) | <5 – 15 patients
5–14 – 22 patients ≥15 – 12 patients |
5–14 – 22 patients
≥15 – 12 patients |
5–14 – 13 patients
≥15 – 12 patients |
| Pulmonary function tests | |||
| FEV1 (% predicted) | 89.3 ± 23.9 | 94.8 ± 23.6 | 96.3 ± 26.4 |
| FVC (% predicted) | 86.1 ± 18.9 | 89.8 ± 18.4 | 91.2 ± 20.4 |
| FEV1/FVC (%) | 80.3 ± 9.6 | 81.6 ± 9.3 | 81.1 ± 10.5 |
| TLC (% predicted) | 84.4 ± 14.8 | 85.5 ± 14.5 | 87.3 ± 15.3 |
| DLCO (% predicted) | 65.8 ± 18.6 | 67.5 ± 18.8 | 61.3 ± 15.9 |
| Six-minute walk test | |||
| Distance (meters) | 405.0 ± 124.8 | 401.8 ± 113.9 | 373.2 ± 94.4 |
| SpO2 before (%) | 95.5 ± 2.5 | 95.7 ± 2.2 | 95.7 ± 1.5 |
| SpO2 after (%) | 87.4 ± 6.1 | 87.5 ± 5.8 | 86.5 ± 6.4 |
| Blood gas analysis | |||
| PaO2 (mmHg) | 79.6 ± 10.7 | 79.1 ± 10.9 | 78.2 ± 10.5 |
| PaCO2 (mmHg) | 38.7 ± 5.1 | 39.2 ± 5.3 | 39.2 ± 5.9 |
| Fibrosis score | 9.3 ± 3.4 | 8.5 ± 3.1 | 8.8 ± 3.3 |
| ESS | 6.7 ± 5.2 | 6.6 ± 4.6 | 8.1 ± 4.7 |
| >11 | 9 (18.4) | 5 (14.7) | 5 (20.0) |
| <11 | 40 (81.6) | 29 (85.3) | 20 (80.0) |
| Polysomnography III | |||
| AHI (events/h) | 11.3 ± 9.9 | 15.0 ± 9.8 | 17.1 ± 10.5 |
| Apnea index (events/h) | 4.4 ± 5.1 | 5.8 ± 5.5 | 5.9 ± 6.3 |
| Hypopnoea (events/h) | 7.0 ± 7.3 | 9.2 ± 7.8 | 11.2 ± 8.0 |
| ODI (events/h) | 11.5 ± 10.7 | 15.2 ± 11.1 | 17.5 ± 11.5 |
| 10 events/h | 23 (46.9) | 23 (67.6) | 20 (80.0) |
| 10 events/h | 26 (53.1) | 11 (32.4) | 5 (20.0) |
| Minimum SpO2 (%) | 83.0 ± 6.9 | 81.5 ± 7.6 | 80.1 ± 7.4 |
| Average SpO2 (%) | 92.9 ± 2.9 | 92.7 ± 3.0 | 92.1 ± 3.0 |
| ST<90% (%) | 14.4 ± 24.7 | 16.9 ± 27.5 | 21.9 ± 30.0 |
| 20% | 12 (24.5) | 10 (29.4) | 10 (40.0) |
| 20% | 37 (75.5) | 24 (70.6) | 15 (60.0) |
All data are given as the mean ± SD or n (%). ESS, Epworth sleepiness score; OSA, obstructive sleep apnoea; PAP, positive airway pressure; AHI, apnoea-hypopnoea index; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; TLC, total lung capacity; DLCO, diffusing capacity of lung for carbon monoxide; ODI, oxygen desaturation index; ST<90%, sleep time with SpO2 below 90%.