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Screening of Prestwick Chemical Library® on D2–Gαi1 and D2–Gαo. A and B, 1200 compounds were tested at the same concentration (5 μm) on cells co-expressing D2–NP/Gαi1–LgBN-term or Gαo–LgB143d. Results are expressed as the ratio over vehicle (DMSO)-treated (compounds) cells.
