Table 1.
Patient demographics
| Primary IAC alone (n = 34) | Primary IAC with IvitC (n = 20) | p values | Total patients (n = 54) | |
|---|---|---|---|---|
| Mean age at presentation, months Sex | 17 (13, 2–59) | 50 (36, 5–278) | 0.02 | 29 (18, 2–278) |
| Sex | ||||
| Male | 21 (62) | 13 (65) | 0.99 | 34 (63) |
| Female | 13 (38) | 7 (35) | 20 (37) | |
| Race | ||||
| Caucasian | 21 (62) | 14 (70) | 0.23 | 35 (65) |
| African American | 3 (9) | 4 (20) | 7 (13) | |
| Asian | 4 (12) | 0 (0) | 4 (7) | |
| Hispanic | 4 (12) | 1 (5) | 5 (9) | |
| Middle Eastern | 1 (3) | 0 (0) | 1 (2) | |
| Indian | 1 (3) | 1 (5) | 2 (4) | |
| Study eye | ||||
| OD | 18 (53) | 11 (55) | 0.55 | 29 (54) |
| OS | 16 (47) | 9 (45) | 25 (46) | |
| Laterality | ||||
| Unilateral retinoblastoma | 33 (97) | 20 (100) | 0.63 | 53 (98) |
| Bilateral retinoblastoma | 1 (3) | 0 (0) | 1 (2) | |
| Genetic testing | ||||
| Somatic mutation | 22 (65) | 15 (75) | 0.63 | 37 (69) |
| Germline mutation | 7 (21)a | 2 (10) | 9 (17)a | |
| Not available | 5 (15) | 3 (15) | 8 (15) | |
Figures in parentheses are percentages or median and range. Bold values indicate significant p values. IAC, intra-arterial chemotherapy; IvitC, intravitreal chemotherapy.
a
One patient had 13q deletion syndrome.