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. Author manuscript; available in PMC: 2019 Oct 22.
Published in final edited form as: Biochem J. 2018 Oct 22;475(20):3221–3238. doi: 10.1042/BCJ20180424

Figure 2. IDH1 dimeric structure (PDB: 4KZO [31]).

Figure 2.

α-Helices 4, 8, 10, and 11 are labeled for reference and colored in yellow (monomer A, helices 4, 10, and 11) and orange (monomer B and helix 8). The NADP+- and Ca2+-binding sites are expanded in the labeled sub-panels. Calcium is shown as a pink sphere. NADP+ is colored based on atoms, with nitrogen (blue), oxygen (red), phosphorus (orange), and carbon (gray) shown. Image was generated with PyMol [63].