Table 1. Six candidate genes revealed using the array.
Beta value | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Mean | Mean | Meth | |||||||||
Gene name | Normal | AIS | Invasive | AIS | Invasive | Diff | |||||
1 | 2 | 1 | 2 | 3 | 1 | 2 | 3 | ||||
ZYG11A | 0.72 | 0.74 | 0.8 | 0.71 | 0.64 | 0.52 | 0.51 | 0.56 | 0.72 | 0.53 | 0.19 |
SFN | 0.59 | 0.63 | 0.36 | 0.55 | 0.46 | 0.25 | 0.27 | 0.41 | 0.46 | 0.31 | 0.15 |
CD1D | 0.81 | 0.84 | 0.84 | 0.81 | 0.76 | 0.86 | 0.71 | 0.52 | 0.8 | 0.70 | 0.11 |
LOC10099657 | 0.63 | 0.66 | 0.36 | 0.54 | 0.46 | 0.18 | 0.27 | 0.19 | 0.45 | 0.21 | 0.24 |
GORASP2 | 0.87 | 0.83 | 0.8 | 0.77 | 0.61 | 0.82 | 0.44 | 0.44 | 0.73 | 0.57 | 0.16 |
MIR656 | 0.77 | 0.8 | 0.76 | 0.74 | 0.75 | 0.71 | 0.62 | 0.63 | 0.75 | 0.65 | 0.1 |
Beta value represents the methylation percentage on a scale of 0-1. All 6 genes show at least a 10% methylation difference between AIS and invasive adenocarcinoma.