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. 2019 Mar 1;10(18):1704–1715. doi: 10.18632/oncotarget.26722

Table 1. Patient clinicopathological characteristics and their association with overall survival and disease free survival using Kaplan-Meier analysis and log-rank Chi-squared test in 70 metastatic colorectal cancer patients.

Characteristics N OS in years
(mean ± SE)
95% CI P-value
(χ2-test)
DFS in months
(mean ± SE)
95% CI P-value
(χ2-test)
Age in years
 ≤70 19 5.478 ± 0.527 4.446–6.511 NS 58.737 ± 8.250 42.567–74.907 NS
 >70 51 5.785 ± 0.361 5.078–6.492 81.460 ± 6.288 69.136–93.785
Gender
 Male 40 5.930 ± 0.415 5.117–6.743 NS 78.636 ± 7.630 63.682–93.590 NS
 Female 30 5.476 ± 0.450 4.593–6.359 75.558 ± 8.212 59.464–91.653
Tumour Site
 Right colon 35 5.600 ± 0.449 4.720–6.480 NS 78.968 ± 8.184 62.927–95.008 NS
 Left colon 35 5.843 ± 0.419 5.022–6.663 77.017 ± 7.269 62.770–91.265
T stage
 T4 18 5.477 ± 0.695 4.116–6.839 NS 71.000 ± 9.247 52.876–89.124 NS
 <T4 52 5.783 ± 0.342 5.113–6.453 76.092 ± 6.519 63.315–88.868
N stage
 N2 41 3.971 ± 0.308 3.368–4.574 0.004 36.489 ± 4.702 27.273–45.706 0.0003
 <N2 19 6.047 ± 0.329 5.401–6.693 88.842 ± 5.839 77.397–100.286
M stage
 M0 62 5.832 ± 0.315 5.214–6.450 NS 79.917 ± 5.951 68.252–91.581 NS
 M1 8 4.208 ± 0.601 3.031–5.386 45.429 ± 6.432 32.822–58.035
LVI
 Absent 48 5.949 ± 0.349 5.265–6.632 NS 82.441 ± 6.933 68.851–96.030 NS
 Present 22 5.142 ± 0.568 4.029–6.255 57.516 ± 6.191 45.381–69.650
Grade
 G3 41 5.869 ± 0.464 4.960–6.779 NS 74.818 ± 7.324 60.463–89.173 NS
 <G3 29 5.592 ± 0.408 4.792–6.392 79.061 ± 8.776 61.860–96.262
Chemotherapy
 No 17 5.250 ± 0.618 4.040–6.460 NS 58.063 ± 8.071 42.244–73.881 NS
 Yes 43 6.012 ± 0.450 5.257–6.766 80.511 ± 6.888 67.010–94.011