Table 1. Patient clinicopathological characteristics and their association with overall survival and disease free survival using Kaplan-Meier analysis and log-rank Chi-squared test in 70 metastatic colorectal cancer patients.
Characteristics | N | OS in years (mean ± SE) |
95% CI |
P-value (χ2-test) |
DFS in months (mean ± SE) |
95% CI |
P-value (χ2-test) |
---|---|---|---|---|---|---|---|
Age in years | |||||||
≤70 | 19 | 5.478 ± 0.527 | 4.446–6.511 | NS | 58.737 ± 8.250 | 42.567–74.907 | NS |
>70 | 51 | 5.785 ± 0.361 | 5.078–6.492 | 81.460 ± 6.288 | 69.136–93.785 | ||
Gender | |||||||
Male | 40 | 5.930 ± 0.415 | 5.117–6.743 | NS | 78.636 ± 7.630 | 63.682–93.590 | NS |
Female | 30 | 5.476 ± 0.450 | 4.593–6.359 | 75.558 ± 8.212 | 59.464–91.653 | ||
Tumour Site | |||||||
Right colon | 35 | 5.600 ± 0.449 | 4.720–6.480 | NS | 78.968 ± 8.184 | 62.927–95.008 | NS |
Left colon | 35 | 5.843 ± 0.419 | 5.022–6.663 | 77.017 ± 7.269 | 62.770–91.265 | ||
T stage | |||||||
T4 | 18 | 5.477 ± 0.695 | 4.116–6.839 | NS | 71.000 ± 9.247 | 52.876–89.124 | NS |
<T4 | 52 | 5.783 ± 0.342 | 5.113–6.453 | 76.092 ± 6.519 | 63.315–88.868 | ||
N stage | |||||||
N2 | 41 | 3.971 ± 0.308 | 3.368–4.574 | 0.004 | 36.489 ± 4.702 | 27.273–45.706 | 0.0003 |
<N2 | 19 | 6.047 ± 0.329 | 5.401–6.693 | 88.842 ± 5.839 | 77.397–100.286 | ||
M stage | |||||||
M0 | 62 | 5.832 ± 0.315 | 5.214–6.450 | NS | 79.917 ± 5.951 | 68.252–91.581 | NS |
M1 | 8 | 4.208 ± 0.601 | 3.031–5.386 | 45.429 ± 6.432 | 32.822–58.035 | ||
LVI | |||||||
Absent | 48 | 5.949 ± 0.349 | 5.265–6.632 | NS | 82.441 ± 6.933 | 68.851–96.030 | NS |
Present | 22 | 5.142 ± 0.568 | 4.029–6.255 | 57.516 ± 6.191 | 45.381–69.650 | ||
Grade | |||||||
G3 | 41 | 5.869 ± 0.464 | 4.960–6.779 | NS | 74.818 ± 7.324 | 60.463–89.173 | NS |
<G3 | 29 | 5.592 ± 0.408 | 4.792–6.392 | 79.061 ± 8.776 | 61.860–96.262 | ||
Chemotherapy | |||||||
No | 17 | 5.250 ± 0.618 | 4.040–6.460 | NS | 58.063 ± 8.071 | 42.244–73.881 | NS |
Yes | 43 | 6.012 ± 0.450 | 5.257–6.766 | 80.511 ± 6.888 | 67.010–94.011 |