Table 1. Characteristics of the 14 patients of cohort 1, who received adjuvant therapy, subdivided according to relapses.
| Variable | No recurrences (n = 8) | Recurrences (n = 6)1 |
|---|---|---|
| age | 67.5 (48–76) years | 66.5 (55–69) years |
| gender (female: male ratio) | 3:5 | 0:6 |
| cancer cell phospho-ERK score | 2.3 (0–10.5) | 8.6 (0.5–12.5) |
| stromal cell phospho-ERK score | 10.0 (1.5–27.0) | 10.3 (5.0–14.8) |
| TRG | 2.5 (2–3)2 | 3.0 (2–5)3 |
| downstaging (cT-ypT) | 0 (0–1) | 0 (–14–1) |
| pT | 3 (2–3) | 3 (2–4) |
| pN | 1 (0–2) | 1 (0–2) |
| deaths (ratio) | 0:8 | 2:6 |
If not otherwise indicated, numbers refer to medians with total ranges given in brackets.
1 3 patients had liver metastases, 2 had lung metastases and one had disseminated disease.
2 4 TRG2 and 4TRG3.
3 2 TRG2, 3TRG3, 1 TRG5.
4 one patient upstaged during RCT.