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Evolutionary relationships between CLEC4f and other C-type lectins. A Genomic organization of CLEC4F and CD207 genes. Exons are color-coded as in Figure 1. B Sequence similarity between individual regions of the CLEC4F protein and langerin. Amino acid identity (%) in each region is indicated. C Dendrogram based on sequence similarity between group 2 C-type CRDs. Group 2 of the C-type lectin family consists of type II transmembrane receptors (Drickamer and Taylor 2015).
