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. Author manuscript; available in PMC: 2019 Mar 18.
Published in final edited form as: Future Med Chem. 2015;7(3):243–256. doi: 10.4155/fmc.14.168

Figure 8. Preclinical candidates in the validated pharmacophores.

Figure 8

(A) Compound V116517 [59] in pharmacophore M5, 3D and 2D view. (B) Compound A-1165442 [60] in pharmacophore M3, 3D and 2D view. Pharmacophore features: yellow: lipophilic substitution; blue: aromatic ring; red: H-bond acceptor; green: H-bond donor.

For colour images see online: www.future-science.com/doi/full/10.4155/FMC.14.168