. Author manuscript; available in PMC: 2019 Mar 18.

Published in final edited form as: Eur J Pharm Sci. 2018 Jun 22;122:134–143. doi: 10.1016/j.ejps.2018.06.022

Table 1. Results from the stereochemical validation of the homology models.

Model	Dope score	G-factor	Qmean score	Residues in generously allowed or disallowed regions (%)
Human MDR1	−0.633	−0.13	0.68	1.7
Rat MDR1a	−0.795	−0.03	0.70	1.7
Rat MDR1b	−0.703	−0.16	0.65	1.8
Mouse mdr1b	−0.808	−0.06	0.69	2.0