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. Author manuscript; available in PMC: 2019 Mar 18.
Published in final edited form as: Eur J Pharm Sci. 2018 Jun 22;122:134–143. doi: 10.1016/j.ejps.2018.06.022

Table 2. Sequence identity/similarity [%] between human, rat and mouse P-gp.

Human-MDR1 Rat MDR1a Rat MDR1b Mouse mdr1a Mouse mdr1b
Human-MDR1 100 87/93 80/90 86/92 80/90
Rat MDR1a 87/93 100 84/91 94/97 84/92
Rat MDR1b 80/90 84/91 100 82/91 93/97
Mouse mdr1a 86/92 94/97 82/91 100 83/91
Mouse mdr1b 80/90 84/92 93/97 83/91 100