Meesters 1999.
Methods | Single‐centre, non‐blinded, randomised controlled trial (duration: 2 winter seasons 1993‐94 and 1994‐95, October‐April each season) conducted in the Netherlands. 8 dropouts (4 bright white visor light, 3 infrared visor light, 1 no light exposure) | |
Participants | 46 adult outpatients with a history of SAD who were without symptoms at the beginning of the study and were free of drugs Bright white visor light group: n = 18, but participant characteristics of only 14 participants reported: 2 men, mean age 41 years (± 12.7), 12 women, mean age 39.5 years (± 9.3) Infrared visor light group: n = 18, but participant characteristics of only 15 participants reported: 5 men, mean age 35.4 years (± 6.9), 10 women, mean age 36.6 years (± 4.9) No light exposure group: n = 10, but participant characteristics of only 9 participants reported: 4 men, mean age 47.5 years (± 7), 5 women, mean age 39.4 years (± 8) No information about number of prior depressive episodes nor other participant characteristics |
|
Interventions | Bright white visor light (n = 18; 30 minutes/d in the morning except on weekends) versus infrared visor light (n = 18; 30 minutes/d in the morning except on weekends) versus no light exposure (n = 10) from October until April | |
Outcomes | Development of depression (BDI ≥ 13, SIGH‐SAD‐SR ≥ 20), development of severe depression (BDI ≥ 22, SIGH‐SAD‐SR ≥ 40) | |
Notes | Study was not funded by pharmaceutical industry; however, equipment was sponsored by Bio Bright, Inc. Study was identified by searches of electronic databases |
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No information about generation of random sequence provided |
Allocation concealment (selection bias) | Unclear risk | No information about allocation concealment provided |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants were not blinded to treatment |
Blinding of outcome assessment (detection bias) All outcomes | High risk | We assume that the outcome assessment was performed by the participants themselves: "patients stopped participating because of reasons unrelated to their illness, such as a lack of motivation to keep scoring self‐rating scales when in a healthy condition" |
Incomplete outcome data (attrition bias) All outcomes | High risk | 17% of dropouts were not taken into account in the data analysis. No participant characteristics (e.g. age, sex) were reported for these 8 dropouts |
Selective reporting (reporting bias) | Unclear risk | We could not identify a protocol for this study. Therefore, we rated this domain unclear |
Other bias | High risk | Intervention was implemented by participants on their own at their homes |
BDI: Beck Depression Inventory SAD: Seasonal affective disorder SIGH‐SAD‐SR: Hamilton Depression Rating Scale‐Seasonal Affective Disorders self‐rating version