Table 1.
Baseline surgical parameters in CHD patients by ciliary motion and nasal nitric oxide*
| All Surgical Events (n = 95) |
Events with CM Data (n=91) |
Events with nNO Data (n=83) |
|||
|---|---|---|---|---|---|
| Normal (n = 58) |
Abnormal (n = 33) |
Normal (n = 48) |
Low (n = 35) |
||
| Age at Surgery (days) | 14 (7–91) | 11 (6–84) | 30(9–127) | 9 (7–92) | 30 (8–91) |
| P= 0.060 | P=0.23 | ||||
| Preoperative Weight (kg) | 3.7 (3.1–5.0) | 3.4 (3.1–4.7) | 4.3 (3.2–6.1) | 3.7 (3.1–4.9) | 3.5 (3.1–5.1) |
| P= 0.054 | P= 0.99 | ||||
| STS-EACTS category† | 3 (2–4) | 3 (2–4) | 3 (2–4) | 3 (2–4) | 3 (2–4) |
| P= 0.65 | P=0.47 | ||||
| Abn PreOp Sys Fxn‡, n (%) | 21 (22%) | 13 (22%) | 7 (21%) | 2 (4%) | 14 (40%) |
| P= 0.64 | P= 0.004 | ||||
| Single ventricle palliation, n (%) | 40 (42%) | 30 (52%) | 10 (30%) | 14 (29%) | 20 (57%) |
| P= 0.15 | P= 0.061 | ||||
| Surgeon 1, n (%) | 68 (72%) | 41 (71%) | 24 (73%) | 34 (71%) | 26 (74%) |
| P= 0.87 | P= 0.51 | ||||
| CPB Time (min) | 88 (62–115) | 89 (66–112) | 89 (55–134) | 86 (57–120) | 91(65–108) |
| P= 0.32 | P= 0.96 | ||||
| XC Time (min) | 27 (0–53) | 23 (0–44) | 44 (0–54) | 30 (0.8–55) | 26 (0–46) |
| P= 0.36 | P= 0.54 | ||||
| DHCA, n (%) | 28 (30%) | 21 (36%) | 7 (21%) | 14 (29%) | 11 (31%) |
| P= 0.15 | P= 0.83 | ||||
*
Data are median (IQR) or n (%). P values obtained from the linear mixed models and generalized linear mixed model for continuous and categorical variables, respectively.
†
Empirically based mortality stratification, categories of 1–5 with higher numbers implying higher mortality risk, based on of the Society of Thoracic Surgeons (STS) and European Association for Cardiothoracic Surgery (EACTS) Congenital Heart Surgery Database
‡
Abn Preop Sys Fxn = abnormal preoperative systolic ventricular function of systemic ventricle. CPB = cardiopulmonary bypass, XC = aortic cross clamp, DHCA = deep hypothermic circulatory arrest