Table 10.
Studies examining peri-hepatic lymphadenectomy in patients undergoing liver resection for metastatic colon cancer
| Study (n=lymphadenectomy patients) | Neoadjuvant chemo | # LN harvested (range) | % with (+)PHLN | OS (−) PHLN | OS (+) PHLN |
|---|---|---|---|---|---|
| Bennett et al. 2008 (n=59) | 50/59 (85%) | 3.2 (1–11) | 22/59 (37%) | 3-year 75% | 3-year 25% (H&E+), 76% (IHC+) |
| Okuno et al. 2017 (n=174) | 154/174 (89%) | NR | 54/174 (31%) | 71 months | 13.8 months |
| Nanji et al. 2016 (n=103) | 22/103 (21%) | 2.2 (1–15) | 30/103 (29%) | 46 months | 25 months |
| Bradatsch et al. 2016 (n=20) | 15/20 (75%) | 5 (NR) | 0/20 (0%) | NR | NA |
| Pindak et al. 2017 (n=59) | 0/59 (0%) | 4.6 (0–13) | 7/59 (12%) | 67 months | 30 months |
Notes: LN, lymph node; NA, not applicable; NR, not reported; OS, median overall survival; PHLN, peri-hepatic lymph node