Figure 6.

Modified immunophenoscore diagrams derived from Charoentong et al²¹ for pre-treatment (top) and post-treatment (bottom) specimens. The gene or gene set comprising each point around the circle is labeled and grouped in corresponding quadrants. Red to blue color scale represent averaged z-score generated from 166 TCGA GBM samples. Grayscale represents weighted z-score associated with the composite score of each quadrant corresponding to the genes or gene sets within the quadrant. MHC = Major histocompatibility complex-associated and antigen presentation genes; CP = checkpoint molecules; EC = effector cells; SC = suppressor cells.