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. 2019 Feb 3;8(4):e1561120. doi: 10.1080/2162402X.2018.1561120

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Correlation between plasma levels of immune checkpoints (sPD-1, sPD-L1, sBTLA, sBTN3A1and pan-sBTN3A) and PDAC patient overall survival. In Figure 2A, a significant inverse correlation was found between sPD-1 (p < 1.10^–4), sPD-L1 (p = 4.10^–3), sBTN3A1 (p = 3.10^–3), pan-sBTN3A (p = 6.10^–4), sBTLA (p = 3.10^–2) and patient overall survival (OS). The correlation was established using the parametric Pearson correlation coefficient (r). In Figure 2B, the prognostic relevance of each marker was assessed by a univariate survival analysis using the Cox regression model.