Fig. 6.

ECT2 promotes tumor growth in vivo. (A, B) U87 cells pretreated with shNC or shECT2 lentivirus and a lentivirus containing luciferase were implanted into the brains of nude mice, and tumor formation was assessed using bioluminescence imaging at days 0, 6, 12, 18, 24, and 30 after implantation. (C) Overall survival was determined using Kaplan–Meier survival curves, and a log-rank test was used to assess the statistical significance of the differences. (D, E) Tumor volume in the shECT2 group was significantly diminished based upon hematoxylin and eosin histology.