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. 2018 Nov 8;20(4):537–545. doi: 10.1080/15384047.2018.1537999

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Figure 3. — Chemokine signaling pathways are involved in FOXP1-mediated effect.

(a) Hierarchical clustering analysis reveals the alterations of transcripts in A549 cells treated with control or FOXP1 siRNA. (b) KEGG analysis of those significantly changed genes shows their enrichment in chemokine signaling pathway. (c and d)　The heatmap of representative genes (c) and the RT-PCR validations (d), showing the alterations of CCR1, ADCY5, GNG7, VAV3, and PLCB1 after the knockdown of FOXP1. * p < 0.05, *** p < 0.001.