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. 2019 Feb 11;18(4):511–522. doi: 10.1080/15384101.2019.1578145

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Figure 6. — Chromatin accessibility changes of acid-adapted SW620 cells The SW620-NA and SW620-AA cells were subjected to ATAC-seq. The differential peaks were then analyzed. (a) The upregulated DGKB gene region is only opened in SW620-AA cells, and the downregulated PCDH19, CNKSR3, GXYLT2, IL8, UTRN gene regions were closed in SW620-AA cells. (b) Distribution of peaks only opened in SW620-AA cells, only opened in SW620-AA cells, and the peaks without changes. (c) Homer known motif enrichment for peaks detected in SW620-AA cells. The top 10 enriched transcription factors were listed. (d) Homer known motif enrichment for peaks detected in SW620-NA cells. The top 10 enriched transcription factors were listed.