Figure 3.

CUL4B promoted DLBCL cell growth. a and b Cell proliferation was assayed by CCK8. CUL4B depletion markedly decreased cell viability (mean ± SD, n = 3, *P < 0.05, **P < 0.01). c and d Enforced CUL4B expression promoted cell viability in DLBCL cell lines (mean ± SD, n = 3, *P < 0.05, **P < 0.01). e and f CUL4B-deletion induced cell cycle arrest at G0/G1 phase in LY1 and LY8 cells. Cell cycle distribution was detected by flow cytometry (mean ± SD, n = 3, *P < 0.05, **P < 0.01, ***P < 0.001).