Table 3.

Serum concentrations of TNF-α in the STZ-induced diabetic rats treated with adalimumab when compared with the controls

Groups	TNF-α (ng/L)
Group 1 (n = 7)	20.71 (0.35)
Group 2 (n = 7)	37.90 (0.27)
Group 3 (n = 7)	25.89 (0.12)
Group 4 (n = 7)	12.44 (0.38)
F statistic	1280.034
P-value	< 0.001
Post-hoc using a pair-wise comparison
Group comparison	P-values
Group 1 versus Group 2	< 0.001
Group 1 versus Group 3	< 0.001
Group 1 versus Group 4	< 0.001
Group 2 versus Group 3	< 0.001
Group 2 versus Group 4	< 0.001
Group 3 versus Group 4	< 0.001

Values are mean (SEM); n = number of subjects; group 1 = obese, diabetic, treated rats; group 2 = obese, diabetic, untreated rats; group 3 = obese, non-diabetic, control rats; group 4 = non-obese, non-diabetic, control rats