Figure 10.

Representative photomicrographs of the dorsomedial prefrontal cortex of Wistar rats showing the external granular layer (II), external pyramidal layer (III) and the internal granular layer (IV). A = control, B = corn oil (CO), C = cuprizone (CPZ), D = cuprizone then kolaviron (CPZ then Kv) and E = kolaviron then cuprizone (Kv then CPZ). A and B showed normal cortical delineation and cellular density while C showed poor cortical delineation with reduced cellular density. D and E showed typical cortical delineation but reduced cellular density relative to A and B. H & E ×100