Table 2.
Irradiated (1.5 Gy + 12 Gy) nude mice that received different hormone-suppression treatments were transplanted with cryopreserved prepubertal monkey testicular cells; resulting recipient testes weights at 8 weeks after transplantation are shown. Values given as mean ± SE (number of testes). (*P<0.05; comparison of transplanted vs untransplanted, t test).
| Hormone Treatment |
Cells injected (× 105) | Testis weight (mg) | |
|---|---|---|---|
| Not transplanted (sham) |
Transplanted | ||
| None (Sham) | 4.1 ± 0.4 | 30.5 ± 2.8 (5) | 41.5 ± 3.6 (6) |
| GnRH-ant | 3.4 ± 0.6 | 30.9 ± 1.1 (11) | 35.1 ± 2.2 (11) |
| GnRH-ant+Flutamide | 3.6 ± 0.3 | 28.6 ± 1.2 (8) | 35.9 ± 2.5 (13) |
| GnRH-ant+FSH | 3.0 ± 0.3 | 27.9 ± 1.8 (11) | 36.4 ± 2.3 (9)* |