Table 1.

The parameters of exercise dosage used in existing studies evaluating the effect of aerobic exercise on concussion outcomes.

Lead Author	Exercise frequency	Exercise duration	Intensity	Intervention length	Mode of exercise	Timing of program initiation
Dobney (20)	Daily	20 – 30 minutes/day	Perceived level of effort corresponding to target HR zone	N/A	Stationary bike or treadmill	3–4 weeks post-concussion (mean=28 days post-injury)
Chan (26)	N/A	15 minutes/day	60% of age-predicted maximum HR	6 weeks	Stationary bike or treadmill	≥ 4 weeks post-concussion
Chrisman (11)	N/A	Maximum 20 minutes/day	80% of symptom exacerbation HR	> 1 week	N/A	≥ 1 month and < 300 days post-concussion
Grool (21)	N/A	N/A	Self-reported as none, light, moderate, or full physical activity	7 days	N/A	Within 7 days of concussion
Moore (24)	3–5 days/week	20–30 minutes/day	60–80% of symptom exacerbation HR	6 months	Stationary bike	Median= 107 days postconcussion Range= 14–992 days
Grabowski (12)	5–6 days/week	Duration achieved during initial exercise test	80% of symptom exacerbation HR	Median = 84 days Range = 7–266 days	Patient preference	≥ 3 weeks and <36 weeks post-concussion Median = 41 days post-concussion
Cordingley (9)	5 days/week	20 minutes/day	80% of symptom exacerbation HR	Until return-to-play or specialist referral	N/A	≥ 1 month post-concussion Median = 35 days
Kurowski (13)	5–6 days/week	80% of the exercise test duration that exacerbated symptoms	Gradual increase to Borg RPE that exacerbates symptoms	6 weeks	Stationary bike	4–16 weeks post-concussion
Clausen (8)	5–6 days/week	20 minutes/day	80% of symptom exacerbation HR	12 weeks	Treadmill	6–12 weeks post-concussion
Gagnon (6)	Daily	20 – 30 minutes/day	60% of age-predicted HR maximum	Median=5.5 weeks Range=2–15.2 weeks	Stationary bike or treadmill	≥ 4 weeks post-concussion
Leddy (7)	6 days/week	20 minutes/day	80% of symptom exacerbation HR	12 weeks	N/A	≥ 6 weeks and < 12 months post-concussion

Note: N/A (Not available), HR (heart rate), RPE (rating of perceived exertion).