Table 2.
Crude and adjusted odds ratios of factors that were independently associated with hospital admission due to hypoglycemic complication, using multivariate analysis
| Variables | Crude OR (95%CI) | P-value | Adjusted OR (95%CI)1 | P-value |
| Age (yr) | ||||
| 65-75 | Reference | Reference | ||
| > 75 | 1.87 (1.51-2.32) | < 0.001 | 1.79 (1.37-2.35) | < 0.001 |
| Gender | ||||
| Male | Reference | Reference | ||
| Female | 1.64 (1.27-2.11) | < 0.001 | 1.63 (1.20-2.21) | < 0.01 |
| Duration of diabetes (yr) | 1.02 (1.01-1.03) | 0.04 | ||
| Hypertension | 1.48 (1.04-2.11) | 0.03 | 1.63 (1.04-2.56) | 0.03 |
| Dyslipidemia | 1.10 (0.87-1.39) | 0.42 | ||
| Cancer | 0.66 (0.16-2.68) | 0.56 | ||
| Dementia | 6.27 (2.13-18.43) | 0.001 | 6.98 (1.80-26.98) | < 0.01 |
| Depression | 0.29 (0.04-2.11) | 0.22 | ||
| Cerebrovascular disease | 1.31 (0.81-2.12) | 0.28 | ||
| Cardiovascular disease | 1.33 (0.97-1.83) | 0.08 | ||
| Peripheral artery disease | 2.48 (1.07-5.72) | 0.03 | ||
| Peripheral neuropathy | 1.24 (0.75-2.03) | 0.40 | ||
| Diabetic retinopathy | 1.51 (1.04-2.20) | 0.03 | 1.45 (0.93-2.24) | 0.10 |
| Smoking | 0.58 (0.25-1.30) | 0.18 | ||
| Insulin | 3.36 (2.71-4.15) | < 0.001 | 3.47 (2.61-4.60) | < 0.001 |
| BMI (kg/m2) | ||||
| < 17.5 | 1.80 (1.20-2.71) | <0.01 | 1.80 (1.12-2.90) | 0.02 |
| 17.5-22.9 | Reference | Reference | ||
| 23.0-27.9 | 0.54 (0.43-0.69) | < 0.001 | 0.44 (0.33-0.60) | < 0.001 |
| > 28.0 | 0.39 (0.27-0.57) | < 0.001 | 0.30 (0.19-0.48) | < 0.001 |
| HbA1C (%) | ||||
| < 7.0 | Reference | Reference | ||
| 7.0-8.5 | 1.42 (1.05-1.92) | 0.02 | 1.41 (1.03-1.93) | 0.01 |
| ≥ 8.5 | 1.97 (1.45-2.68) | < 0.001 | 1.49 (1.06-2.09) | 0.02 |
| eGFR (mL/min per 1.73 m2) | ||||
| ≥ 60 | Reference | Reference | ||
| < 60 | 2.59 (1.97-3.39) | < 0.001 | 1.53 (1.12-2.11) | 0.01 |
1
Adjusted for age, gender, duration of diabetes mellitus, hypertension, dyslipidemia, cancer, dementia, depression, cerebrovascular disease, coronary artery disease, peripheral artery disease, peripheral neuropathy, diabetic retinopathy, smoking, insulin, body mass index, hemoglobin A1C and estimated glomerular filtration rate using backward (Wald) method. BMI: Body mass index; HbA1C: Hemoglobin A1C; eGFR: Estimated glomerular filtration rate; OR: Odds ratio; 95%CI: 95% confidence interval.