Table 1. The association of lncRNA MALAT1 polymorphisms and CAD risk1.
| SNPs | CON (%) | CAD (%) | CAD compared with CON | |
|---|---|---|---|---|
| P2 | OR (95% CI) | |||
| MALAT1 rs4102217 | ||||
| GG | 275 (77.9) | 243 (72.1) | 1 (Ref) | |
| GC | 78 (22.1) | 94 (27.9) | 0.076 | 1.37 (0.97–1.94) |
| CC | 11 (3.8) | 8 (3.2) | 0.705 | 0.84 (0.33–2.12) |
| CC+GC compared with GG | 0.120 | 1.30 (0.93–1.82) | ||
| CC compared with GC+GG | 0.575 | 0.77 (0.31–1.93) | ||
| C compared with G | 0.233 | 1.20 (0.89–1.60) | ||
| PHWE2 | 0.068 | |||
| MALAT1 rs619586 | ||||
| AA | 309 (87.0) | 293 (85.4) | 1 (Ref) | |
| AG | 46 (13.0) | 50 (14.6) | 0.531 | 1.15 (0.75–1.77) |
| GG | 2 (0.6) | 1 (0.3) | 0.667 | 0.59 (0.05–6.56) |
| GG+AG compared with AA | 0.589 | 1.13 (0.74–1.72) | ||
| GG compared with G+AA | 0.628 | 0.55 (0.05–6.12) | ||
| G compared with A | 0.671 | 1.09 (0.73–1.63) | ||
| PHWE2 | 0.839 | |||
Abbreviations: CI, confidence interval; CON, control, OR, odds ratio; NCBI Ref, the reference frequencies of these polymorphisms in Beijing Han, China in NCBI database.
1Using logistic regression adjusted by sex and age.
2Means Hardy−Weinberg Equilibrium in population.