Table 6. Cumulative effect of the interacting factors of MALAT1 SNPs on CAD.

Number of interacting genotypes	Total population
	Cases/controls	P1 value	OR (95% CI)
MALAT1 rs41022173-rsMALAT1 rs619568-smoking-drinking
0	56/75		1 (Ref)
1	134/92	0.009	1.84 (1.17–2.90)
2	105/127	0.904	0.97 (0.60–1.58)
3	31/51	0.266	0.70 (0.38–1.31)
4	4/3	0.610	1.50 (0.32–7.13)
	Ptrend=0.198

¹, Adjusted by sex and age.

Values in bold represent statistical significance.