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. 2019 Mar 12;10:205. doi: 10.3389/fneur.2019.00205

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Copyright © 2019 Birkner, Loos, Gollan, Steffen, Wasser, Ruck, Meuth, Zipp and Bittner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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No significant correlation between neurofilament light chain levels and sICAM-5. (A) ICAM-5 was correlated with NfL concentrations (pg/ml) in the cerebrospinal fluid and the serum of SPMS patients (n = 7–8). (B) ICAM-5 was correlated to NfL concentrations (pg/ml) in the cerebrospinal fluid and the serum of PPMS patients (n = 7–8). (C) ICAM-5 was correlated to NfL concentrations (pg/ml) in the cerebrospinal fluid and the serum of pooled SPMS and PPMS patients (n = 14–16). For all figures: Data was tested for normality using Shapiro-Wilk normality test and Pearson's or Spearman's r and p-values was determined accordingly.