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. 2019 Feb 13;79(4):365–379. doi: 10.1007/s40265-019-1064-1

Table 2.

Quantification of proteinuria

(adapted from Kidney Disease: Improving Global Outcomes 2012 chronic kidney disease guidelines [4])

Quantification method Normal or mildly increased Moderately increased Severely increased Nephrotic range
Dipstick Negative to trace Trace to + + or greater +++ or greater
ACR
 mg/mmol < 3 3–30 > 30 > 220
 mg/g < 30 30–300 > 300 > 2200
PCR
 mg/mmol < 15 15–50 > 50 > 300
 mg/g < 150 150–500 > 500 > 3000
24-h urinary protein (g/day) < 0.15 0.15–0.5 > 0.5 > 3

Relationship between measurement methods are not exact and will depend on multiple variables

ACR albumin-to-creatinine ratio, PCR protein-to-creatinine ratio