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. 2018 Dec 17;174(2):505–514. doi: 10.1007/s10549-018-05090-y

Table 1.

Change in systemic therapy 1990–2011: stage I–III (n = 8292)

1990–1998 1999–2004 2005–2011 p value
N (%) N (%) N (%)
Adjuvant chemotherapy (n = 4426) 1230 (52%) 1271 (53%) 1925 (55%) 0.134
Taxane therapy (n = 2130) 171 (14%) 622 (49%) 1337 (70%) < 0.001
Neoadjuvant therapy: chemotherapy patients (n = 618) 150 (12%) 157 (12%) 311 (16%) 0.001
Hormone therapy: HR+ positive patients (n = 5602) 1317 (70%) 1677 (83%) 2608 (87%) < 0.001
Trastuzumab therapy: HER2 positive patients (n = 515) 86 (29%) 429 (90%) < 0.001