Table 4.

Cox proportional hazards model of distant recurrence among stage I–III BC patients 1990–2011 (n = 8292)

	HzR (95% CI)	p value
Stage I	Reference
Stage II	3.18 (2.64, 3.84)	< 0.001
Stage III	10.26 (8.38, 12.56)
Diagnosis year 1990–1998	Reference
Diagnosis year 1999–2004	0.61 (0.52, 0.71)	< 0.001
Diagnosis year 2005–2011	0.46 (0.39, 0.55)
Positive hormone receptor status	Reference
Negative hormone receptor status	1.54 (1.33, 1.78)	< 0.001
Mammography-detected BC	Reference
Symptom-detected BC	1.51 (1.29, 1.78)	< 0.001
Age 40 + years	Reference
Age 20–39 years	1.26 (1.04, 1.51)	0.017
HR/HER2 status comparisons after 1998 (n = 5387)
HR+/HER2−	Reference
HR+ or HR−/HER2+	0.98 (0.76, 1.26)	0.871
HR−/HER2−	1.97 (1.57, 2.47)	< 0.001

Adjusted for self-reported race and listed by order of entry into the model

CI confidence intervals, HzR hazard ratio