Table 2.
Results of 79 pathologists responding to our questionnaire on histologic grading of ductal carcinoma in situ (DCIS) of the breast
| n (%) | |||
|---|---|---|---|
| Total (n = 79) | Breast pathologist (n = 37) | General pathologist (n = 42) | |
| Laboratory | |||
| Academic | 15 (19.0%) | 11 (29.7%) | 4 (9.5%) |
| Peripheral | 64 (81.0%) | 26 (70.3%) | 38 (90.5%) |
| Years of experience | |||
| 0–5 | 28 (35.4%) | 11 (29.7%) | 17 (40.5%) |
| 6–10 | 15 (19.0%) | 6 (16.2%) | 9 (21.4%) |
| 11–20 | 17 (21.5%) | 9 (24.3%) | 8 (19.0%) |
| >20 | 19 (24.1%) | 11 (29.7%) | 8 (19.0%) |
| Based on which guideline or reference do you grade DCIS?a | |||
| Holland et al. [21] | 28 (35.4%) | 14 (37.8%) | 14 (33.3%) |
| Pinder et al. [22] | 16 (20.3%) | 9 (24.3%) | 7 (16.7%) |
| Intuition | 16 (20.3%) | 8 (21.6%) | 8 (19.0%) |
| WHO [23] | 11 (13.9%) | 5 (13.5%) | 6 (14.3%) |
| I do not know | 4 (5.1%) | 0 (0.0%) | 4 (9.5%) |
| Tavassoli et al. [24] | 3 (3.8%) | 1 (2.7%) | 2 (4.8%) |
| Van Nuys (Silverstein et al. [25]) | 2 (2.5%) | 1 (2.7%) | 1 (2.4%) |
| College of American Pathologists Guidelines [26] | 1 (1.3%) | 0 (0.0%) | 1 (2.4%) |
| Combination (n.o.s.) | 1 (1.3%) | 1 (2.7%) | 0 (0.0%) |
| How do you grade a DCIS of heterogeneous differentiation? | |||
| Based on the highest grade | 60 (76.0%) | 28 (75.7%) | 32 (76.2%) |
| I report the percentages of each grade | 9 (11.4%) | 4 (10.8%) | 5 (11.9%) |
| Based on the predominant grade | 7 (8.9%) | 4 (10.8%) | 3 (7.1%) |
| Not within the protocol | 3 (3.8%) | 1 (2.7%) | 2 (4.8%) |
n.o.s. not otherwise specified
aMultiple answers possible (n = 82)