Fig. 3. CHBP improved left ventricular function and remodeling.

Representative M-mode images and echocardiographic parameters in control and CHBP-treated mice after 8-weeks ischemia injury are shown (a). The left ventricular end-diastolic volume was significantly larger in the control group compared to that in the CHBP group (b). The ejection fraction was also remarkably improved in the CHBP group (c). The systolic (d) and diastolic (e) left ventricular anterior wall were significantly thicker by CHBP treatment, as well as the systolic (f) and diastolic (g) posterior wall thickness. The dot line represents baseline parameters, which were measured by sham mice