Table 2.
Top 50 transcripts depleted in mpeg1:GFP+cells compared to GFP− retinal cells at 7 days post ouabain lesion, sorted by FDR.
| moderated log2FC | FDR | GENE NAME | SYMBOL | ZFIN | ENTREZID |
|---|---|---|---|---|---|
| −9.902497402 | 4.52E-39 | prostaglandin D2 synthase b, tandem duplicate 2 | ptgdsb.2 | ZDB-GENE-030911-3 | 751701 |
| −5.354755121 | 1.18E-29 | arrestin 3a, retinal (X-arrestin) | arr3a | ZDB-GENE-040718-102 | 436678 |
| −8.788432384 | 4.96E-27 | biglycan b | bgnb | ZDB-GENE-040426-21 | 792197 |
| −5.457182226 | 3.46E-24 | phosphodiesterase 6 H, cGMP-specific, cone, gamma, paralog a | pde6ha | ZDB-GENE-040426-1754 | 393758 |
| −5.100382872 | 1.57E-23 | guanine nucleotide binding protein (G protein), beta polypeptide 3b | gnb3b | ZDB-GENE-040426-2280 | 406483 |
| −9.975719622 | 1.35E-22 | ba1 globin | ba1 | ZDB-GENE-990415-18 | 30216 |
| −5.337784049 | 1.35E-22 | recoverin 2 | rcvrn2 | ZDB-GENE-030131-7590 | 335650 |
| −6.435756586 | 1.46E-22 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b | gngt2b | ZDB-GENE-091020-4 | 797361 |
| −6.397569387 | 8.07E-22 | opsin 1 (cone pigments), short-wave-sensitive 1 | opn1sw1 | ZDB-GENE-991109-25 | 30582 |
| −6.09923235 | 8.44E-21 | phosphodiesterase 6 C, cGMP-specific, cone, alpha prime | pde6c | ZDB-GENE-040426-1664 | 393845 |
| −8.761307281 | 1.03E-19 | ral guanine nucleotide dissociation stimulator-like 3a | rgl3a | ZDB-GENE-101130-1 | 100149956 |
| −7.8244016 | 1.77E-19 | MYCN proto-oncogene, bHLH transcription factor | mycn | ZDB-GENE-020711-1 | 252851 |
| −6.044518098 | 2.44E-19 | insulin-like growth factor binding protein 5b | igfbp5b | ZDB-GENE-040319-2 | 403039 |
| −8.029031786 | 3.45E-19 | solute carrier family 38, member 4 | slc38a4 | ZDB-GENE-041010-14 | 449771 |
| −5.288624547 | 3.45E-19 | aquaporin 1a (Colton blood group), tandem duplicate 1 | aqp1a.1 | ZDB-GENE-030131-7764 | 335821 |
| −5.836694213 | 6.71E-19 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a | gngt2a | ZDB-GENE-030131-7595 | 335655 |
| −7.439163089 | 1.13E-18 | NA | NA | NA | NA |
| −4.079039413 | 1.45E-18 | fatty acid binding protein 7, brain, a | fabp7a | ZDB-GENE-000627-1 | 58128 |
| −6.971250125 | 3.09E-18 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 | slc24a2 | ZDB-GENE-060825-277 | 751686 |
| −8.382635563 | 6.75E-18 | unc-119 homolog b (C. elegans) | unc119b | ZDB-GENE-050201-2 | 678653 |
| −8.363908429 | 1.26E-17 | follistatin b | fstb | ZDB-GENE-031118-139 | 566538 |
| −8.099791471 | 1.44E-17 | espin | espn | ZDB-GENE-081105-173 | 567061 |
| −7.466759677 | 4.39E-17 | fatty acid desaturase 2 | fads2 | ZDB-GENE-011212-1 | 140615 |
| −4.673096962 | 6.59E-17 | retinol binding protein 4, like | rbp4l | ZDB-GENE-030131-7591 | 335651 |
| −6.617741567 | 1.62E-16 | synaptotagmin Va | syt5a | ZDB-GENE-040718-110 | 436686 |
| −6.853925862 | 1.83E-16 | peripherin 2a (retinal degeneration, slow) | prph2a | ZDB-GENE-000616-8 | 58085 |
| −4.326891 | 3.67E-16 | midkine a | mdka | ZDB-GENE-990621-1 | 30277 |
| −10.78175227 | 4.55E-16 | T-box 2b | tbx2b | ZDB-GENE-990726-27 | 30253 |
| −10.29982042 | 5.43E-16 | si:ch211-183d21.1 | si:ch211-183d21.1 | ZDB-GENE-030131-8516 | 571430 |
| −7.361502097 | 5.82E-16 | doublecortin-like kinase 2a | dclk2a | ZDB-GENE-050420-170 | 572548 |
| −10.57382742 | 6.16E-16 | protein kinase C and casein kinase substrate in neurons 1a | pacsin1a | ZDB-GENE-050522-155 | 553559 |
| −6.109615504 | 6.38E-16 | zgc:195173 | zgc:195173 | ZDB-GENE-081022-190 | 792613 |
| −10.29473981 | 7.27E-16 | transmembrane protein 108 | tmem108 | ZDB-GENE-091204-397 | 563089 |
| −5.473704873 | 1.73E-15 | opsin 1 (cone pigments), long-wave-sensitive, 2 | opn1lw2 | ZDB-GENE-040718-141 | 436716 |
| −7.717505976 | 2.51E-15 | tight junction protein 2b (zona occludens 2) | tjp2b | ZDB-GENE-040718-58 | 436639 |
| −8.088389566 | 5.77E-15 | retinol binding protein 3 | rbp3 | ZDB-GENE-990415-132 | 30735 |
| −8.358797824 | 6.92E-15 | storkhead box 2a | stox2a | ZDB-GENE-090313-101 | 571741 |
| −5.691417183 | 1.38E-14 | ATPase, Na+/K+ transporting, alpha 1b polypeptide | atp1a1b | ZDB-GENE-001212-5 | 64616 |
| −6.468437477 | 1.87E-14 | collagen type XVIII alpha 1 chain a | col18a1a | ZDB-GENE-030516-3 | 564123 |
| −5.409702873 | 2.17E-14 | solute carrier family 1 (glial high affinity glutamate transporter), member 2b | slc1a2b | ZDB-GENE-030131-7779 | 335836 |
| −8.857169039 | 2.50E-14 | erythrocyte membrane protein band 4.1 like 5 | epb41l5 | ZDB-GENE-030616-450 | 368449 |
| −7.392218598 | 3.00E-14 | si:ch211-81a5.8 | si:ch211-81a5.8 | ZDB-GENE-060503-138 | 560648 |
| −9.889739986 | 4.98E-14 | BOC cell adhesion associated, oncogene regulated | boc | ZDB-GENE-030131-6560 | 334628 |
| −9.997009725 | 5.09E-14 | hairy-related 2 | her2 | ZDB-GENE-980526-274 | 30300 |
| −7.35634514 | 5.33E-14 | si:dkey-126g1.9 | si:dkey-126g1.9 | ZDB-GENE-030131-9862 | 792999 |
| −10.86276442 | 9.44E-14 | collagen, type V, alpha 2a | col5a2a | ZDB-GENE-030616-13 | 564821 |
| −8.375593909 | 9.47E-14 | shroom family member 2a | shroom2a | ZDB-GENE-050208-128 | 386817 |
| −7.42402034 | 1.04E-13 | NA | NA | NA | NA |
| −4.477364135 | 1.08E-13 | ATPase, H+ transporting, lysosomal, V0 subunit cb | atp6v0cb | ZDB-GENE-030131-4127 | 325402 |
| −10.42654367 | 1.69E-13 | si:ch211-285j22.3 | si:ch211-285j22.3 | ZDB-GENE-141216-187 | 336034 |