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. 2019 Mar 12;9:140. doi: 10.3389/fonc.2019.00140

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Copyright © 2019 Piazzi, Prossomariti, Baldassarre, Montagna, Vitaglione, Fogliano, Biagi, Candela, Brigidi, Balbi, Munarini, Belluzzi, Pariali, Bazzoli and Ricciardiello.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Feeding and carcinogenesis protocol. After acclimation (age 8 weeks) feeding protocols were started and maintained for 27 weeks. From week 16 LFD, LFD-MD-MIX, HFWD, and HFWD-MD-MIX mice were subjected to eight intraperitoneal AOM injections. The number of mice “n” in each arm is shown.