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. 2019 Mar 12;9:140. doi: 10.3389/fonc.2019.00140

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Copyright © 2019 Piazzi, Prossomariti, Baldassarre, Montagna, Vitaglione, Fogliano, Biagi, Candela, Brigidi, Balbi, Munarini, Belluzzi, Pariali, Bazzoli and Ricciardiello.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of diets, AOM-treatment and MD-MIX on gut microbiota composition. Genus level average fecal microbiota profiles at time points T1, T2, and T3 for all combinations of diet (LFD and HFWD) and supplementation (MD-MIX), expressed as heatmap with horizontal scaling. Bacterial genera present at a relative abundance >0.05% in at least one sample are plotted. The color scale from blue to brown indicates the z score (i.e., number of standard deviations from the mean, from −3 to 3) for each time point. The heatmap has been generated using the function heatplot within the R package MADE4.