Table 2.
Lung Function Outcomes | Univariate Model |
Model 1* |
Model 2† |
||||||
---|---|---|---|---|---|---|---|---|---|
β | SE | P Value | β | SE | P Value | β | SE | P Value | |
Tptef:Te | −0.004 | 0.001 | 0.01 | −0.004 | 0.002 | 0.01 | −0.004 | 0.002 | 0.01 |
RR, breaths/min | 0.28 | 0.11 | 0.01 | 0.28 | 0.11 | 0.02 | 0.28 | 0.11 | 0.01 |
Vt, ml | −0.02 | 0.06 | 0.77 | 0.001 | 0.05 | 0.97 | 0.001 | 0.05 | 0.97 |
MV, ml/min | 6.68 | 3.94 | 0.09 | 7.26 | 3.76 | 0.05 | 7.21 | 3.77 | 0.05 |
Crs/kg, ml/cm H2O/kg | 0.001 | 0.001 | 0.34 | 0.001 | 0.001 | 0.52 | 0.001 | 0.001 | 0.53 |
Definition of abbreviations: CO = carbon monoxide; Crs/kg = passive respiratory system compliance per kilogram; MV = minute ventilation; RR = respiratory rate; Tptef:Te = ratio of the time to peak tidal expiratory flow to expiratory time.
Models adjusted for child sex, length, weight, and age at examination, and maternal education, ethnicity, and wealth index, per 1 ppm increase in average prenatal CO.
Models additionally adjusted for child birth weight and gestational age at delivery.