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. 2019 Mar 15;199(6):738–746. doi: 10.1164/rccm.201804-0694OC

Table 2.

Estimated Effects of Average Prenatal CO on Infant Lung Function: Linear Regression

Lung Function Outcomes Univariate Model
Model 1*
Model 2
β SE P Value β SE P Value β SE P Value
Tptef:Te −0.004 0.001 0.01 −0.004 0.002 0.01 −0.004 0.002 0.01
RR, breaths/min 0.28 0.11 0.01 0.28 0.11 0.02 0.28 0.11 0.01
Vt, ml −0.02 0.06 0.77 0.001 0.05 0.97 0.001 0.05 0.97
MV, ml/min 6.68 3.94 0.09 7.26 3.76 0.05 7.21 3.77 0.05
Crs/kg, ml/cm H2O/kg 0.001 0.001 0.34 0.001 0.001 0.52 0.001 0.001 0.53

Definition of abbreviations: CO = carbon monoxide; Crs/kg = passive respiratory system compliance per kilogram; MV = minute ventilation; RR = respiratory rate; Tptef:Te = ratio of the time to peak tidal expiratory flow to expiratory time.

*

Models adjusted for child sex, length, weight, and age at examination, and maternal education, ethnicity, and wealth index, per 1 ppm increase in average prenatal CO.

Models additionally adjusted for child birth weight and gestational age at delivery.