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. 2019 Mar 12;10:440. doi: 10.3389/fmicb.2019.00440

FIGURE 1.

FIGURE 1

Differential metabolic profiles of male and female S. japonicum worms between SCID mice and BALB/c mice at 35 days post infection. Principal Component Analysis (PCA) score scatter plots of metabolites obtained from LC-MS/MS fingerprints in ESI+ (A) and ESI- mode (B). Partial least-squares discriminant analysis (PLS-DA) separating metabolites of the four groups of worms and QC sample in ESI+ (C) and ESI– mode (D). IB-MALE denotes the male worms from BALB/c mice, which are marked with green plus sign. IB-FEMALE denotes the female worms from BALB/c mice, which are marked with red triangles. IS-MALE denotes the male worms from SCID mice, which are marked with blue diamonds. IS-FEMALE denotes the female worms from SCID mice, which are marked with purple cross. QC denotes the quality control samples, which are marked with pink triangles. The sample size is 5 in each group of worm samples.