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. 2019 Feb 6;41(1):69–76. doi: 10.1007/s11357-019-00055-5

Table 1.

Demographics, risk factors, and pertinent medications in all patients (N = 60) and in those separated by initial cognitive screening scores. Data include mean/standard deviation for continuous measures and frequency/percentages for categorical measures

Characteristic All participants (n = 60) MoCA < 26 (n = 23) MoCA ≥ 26 (n = 29) P
Min Max Mean SD Min Max Mean SD Min Max Mean SD
Age (years) 50 86 64 7.1 51 86 65.3 7.3 50 75 63.3 7.3 0.31
Count % Count % Count %
Male gender 54 90 23 100 24 83 0.059*
Education 0.40**
 < High school 3 5 2 9 0 0
 High school 16 27 5 22 8 28
 Some college 28 47 12 52 14 48
 College/advanced degree 13 22 4 17 7 24
Smoking status 0.084
 Never 13 22 6 26 4 14
 Former 22 36 5 22 15 52
 Current 25 42 12 52 10 34
Medication
 Antiplatelets 43 72 18 78 19 66 0.31
 Statins 46 77 19 83 23 79 > 0.9*
 ACE inhibitor 28 47 8 35 17 59 0.09
ARBs 7 12 3 13 3 10 > 0.9*
 Beta blocker 32 53 15 65 13 45 0.14
 Calcium channel blocker 22 36 10 43 11 38 0.69
 Diuretic 25 42 12 52 11 38 0.30
 Comorbidities
 Coronary artery disease 20 34 7 30 10 36 0.69
 Atrial fibrillation 1 2 0 0 0 0
 Peripheral artery disease 6 10 2 9 2 7 > 0.9*
 Hypercholesterolemia 53 88 21 91 25 86 0.68*
 Hypertension 55 92 22 96 25 86 0.37*
 Diabetes 28 47 10 43 13 45 0.92

ACE inhibitor angiotensin-converting enzyme inhibitor, ARBs angiotensin II receptor blockers

P value reflects comparison of means, using a two-sample t test, for continuous measures and a comparison of proportions, using a chi-square test, for categorical measures, unless otherwise indicated, between groups defined by initial cognitive screening scores

*Fisher’s exact test

**Cochran-Armitage trend test