Table 2.
Demographic and disease characteristics at the time of secukinumab initiation of patients with AS (N = 78)
| Characteristic | Patients with AS (N = 78) |
|---|---|
| Age | |
| Mean (SD), years | 39.8 (10.8) |
| Median (IQR), years | 38.0 (32.0–45.0) |
| Male, n (%) | 60 (76.9) |
| Race/ethnicity, n (%) | |
| White/non-Hispanic | 54 (69.2) |
| Hispanic | 13 (16.7) |
| Black/non-Hispanic | 8 (10.3) |
| Asian/Pacific Islander | 3 (3.8) |
| Insurance type, n (%) | |
| Commercial/private | 56 (71.8) |
| Medicaid | 13 (16.7) |
| Medicare | 9 (11.5) |
| Military | 1 (1.3) |
| No insurance | 1 (1.3) |
| Unknown/not sure | 1 (1.3) |
| Duration of AS, n (%) | |
| < 1 year | 11 (14.1) |
| 1–2 years | 26 (33.3) |
| 3–5 years | 22 (28.2) |
| 6–10 years | 13 (16.7) |
| > 10 years | 6 (7.7) |
| Physician-assessed disease severity, n (%) | |
| Mild | 7 (9.0) |
| Moderate | 56 (71.8) |
| Severe | 15 (19.2) |
| AS symptoms experienced, n (%)a | 78 (100) |
| Lower back pain | 71 (91.0) |
| Morning stiffness | 65 (83.3) |
| Limited spinal mobility and range of motion | 48 (61.5) |
| Fatigue (e.g., low energy/tired) | 47 (60.3) |
| Nocturnal pain | 45 (57.7) |
| Neck pain | 38 (48.7) |
| Hip pain | 26 (33.3) |
| Enthesitis | 23 (29.5) |
| Peripheral arthritis | 20 (25.6) |
| Dactylitis | 10 (12.8) |
| Inflammatory eye disease | 6 (7.7) |
| Otherb | 1 (1.3) |
| Co-morbidities, n (%)c | |
| Hypertension | 20 (25.6) |
| Anemia | 16 (20.5) |
| Digestive disorders | 12 (15.4) |
| Anxiety | 9 (11.5) |
| Hyperlipidemia | 8 (10.3) |
| Depression | 6 (7.7) |
| Inflammatory eye diseases (e.g., uveitis) | 5 (6.4) |
| Crohn disease | 4 (5.1) |
| Diabetes | 4 (5.1) |
| Psoriasis | 4 (5.1) |
| Ulcerative colitis | 4 (5.1) |
| Malignancyd | 2 (2.6) |
AS ankylosing spondylosis
aMultiple AS symptoms could be selected for each patient except when “None of the above” was selected
bOther symptoms included “psoriasis”
cMultiple co-morbidities could be selected for each patient except if “none of the above” was selected
dMalignancy included “melanoma”