Table 1.
Characteristics | Number of patients (%) |
---|---|
Total | 40 |
median Age, y (range) | 39 (16–61) |
≥ 45 years | 29 (72.5%) |
< 45 years | 11 (27.5%) |
Gender | |
Male | 28 (70.0%) |
Female | 12 (30.0%) |
Histopathological classification | |
Diffuse large B cell lymphoma | 40 (100%) |
Tumor bulk | |
≥ 10 cm | 7 (17.5%) |
Number of prior chemotherapy regimens | |
2 | 6 (15.0%) |
3 | 12 (30.3%) |
4 or more | 22 (55.0%) |
Number of prior chemotherapy cycles | |
6 | 3 (7.5%) |
8 | 5 (12.5%) |
9 or more | 32 (80.0%) |
Previous radiation therapy | |
Yes | 4 (10.0%) |
No | 36 (90.0%) |
B symptoms | 25 (62.5%) |
Extranodal disease | 37 (92.5%) |
Conditioning regiments | |
BEAM | 15 (37.5%) |
CBV | 21 (52.5%) |
LACE | 4 (10.0%) |
Refractory status | |
Primary refractory | 26 (65.0%) |
Relapse refractory | 14 (35.0%) |
ECOG | |
0–2 | 17 (42.5%) |
3–4 | 23 (57.5%) |
Previous rituximab therapy | |
Yes | 37 (92.5%) |
No | 3 (7.5%) |