Table 3.
Multivariate analysis of factors associated with CR rate, PFS, and OS after APBSCT
Covariates | CR | P | PFS | P | OS | P |
---|---|---|---|---|---|---|
OR (95% CI) | HR (95% CI) | HR (95% CI) | ||||
ECOG (≥ 2 vs < 2) | – | – | 2.662 (1.123–6.309) | 0.030 | 3.832 (1.297–11.324) | 0.024 |
Clinical response to high-dose etoposide (yes vs no) | 2.331 (1.481–3.891) | 0.014 | 0.210 (0.069–0.643) | 0.006 | 0.183 (0.062–0.543) | 0.002 |
Conditioning regiments (BEAM vs CVB and LACE) | 2.127 (0.612–4.042) | 0.052 | – | – | – | – |
OR, odds ratio; HR, hazard ratio; 95% CI, 95% confidence interval; statistically significant differences shown in bold; CR, complete remission; OS, overall survival; PFS, disease-free survival