Table 2.
Multivariate analysis of prognostic factors for BCSS before and after PSM.
| Variables | Before PSM | After PSM | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | |
| AGE (YEARS) | ||||||
| < 50 | 1 | 1 | ||||
| ≥50 | 1.041 | 0.961–1.127 | 0.325 | 1.029 | 0.929–1.139 | 0.586 |
| RACE/ETHNICITY | ||||||
| Non-Hispanic white | 1 | 1 | ||||
| Non-Hispanic black | 1.282 | 1.151–1.428 | < 0.001 | 1.354 | 1.189–1.543 | < 0.001 |
| Hispanic (all races) | 1.006 | 0.892–1.133 | 0.928 | 1.072 | 0.923–1.246 | 0.363 |
| Other | 0.836 | 0.720–0.971 | 0.019 | 0.844 | 0.687–1.036 | 0.105 |
| GRADE | ||||||
| Well differentiated | 1 | 1 | ||||
| Moderately differentiated | 1.471 | 1.199–1.803 | < 0.001 | 1.537 | 1.160–2.036 | 0.003 |
| Poorly differentiated/undifferentiated | 1.910 | 1.560–2.339 | < 0.001 | 2.073 | 1.566–2.743 | < 0.001 |
| TUMOR STAGE | ||||||
| T1 | 1 | 1 | ||||
| T2 | 1.372 | 1.256–1.498 | < 0.001 | 1.368 | 1.233–1.517 | < 0.001 |
| NODAL STATUS | ||||||
| N2 | 1 | 1 | ||||
| N3 | 1.682 | 1.558–1.816 | < 0.001 | 1.617 | 1.466–1.784 | < 0.001 |
| HORMONE RECEPTOR STATUS | ||||||
| ER+ and PR+ | 1 | 1 | ||||
| ER+ or PR+ | 1.512 | 1.358–1.583 | < 0.001 | 1.490 | 1.295–1.714 | < 0.001 |
| ER- and PR- | 1.932 | 1.765–2.114 | < 0.001 | 1.833 | 1.636–2.053 | < 0.001 |
| MARITAL STATUS | ||||||
| Unmarried | 1 | 1 | ||||
| Married | 0.861 | 0.797–0.931 | < 0.001 | 0.865 | 0.784–0.954 | 0.004 |
| SURGICAL PROCEDURE | ||||||
| BCS | 1 | 1 | ||||
| MAST | 1.179 | 1.087–1.278 | < 0.001 | 1.124 | 1.023–1.236 | 0.015 |
BCS, breast-conserving surgery; CI, confidence interval; ER, estrogen receptor; HR, hazard ratios; MAST, mastectomy; PR, progesterone receptor; PSM, propensity score matching; T, tumor.