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MR images and the 3D tumor mask of a 47-year-old female with IDH1–wild-type glioblastoma. The color-coded CBF maps (a) in the sagittal, coronal, and axial plane from left to right show a thick and irregular ring hyperperfusion of the tumor covered with a translucent layer representing the 3D ROI. The 3D tumor mask extracted from CBF maps is exactly projected on to the corresponding T2FLAIR (b) and ceT1WI (c).
