Figure 3. Expression of UCP2 in RPE cells with increased chronological age.
A: RT-PCR showed that there was a consistent decrease in mRNA levels of UCP2 with aging at an approximate 0.94 and 0.57 fold changes, respectively between the youngest and oldest donors; B: The protein levels of UCP2 decreased at an approximate 1.24 and 0.36 fold changes with aging in Western blot, respectively between the youngest and oldest donors. Results are expressed as the mean±SE of 3 independent experiments done in triplicates. aSignificantly different from 9-20y (P<0.05).